We have found an IELTS reading simulation exercises--New weapon to fight cancer.
Alok Jha, science correspondent
Thursday January 11, 2007
The Guardian1. British scientists are preparing to launch trials of aradical new way to fight cancer, which kills tumours by infecting them withviruses like the common cold.
2. If successful, virus therapy could eventually form a third pillaralongside radiotherapy and chemotherapy in the standard arsenal against cancer,while avoiding some of the debilitating side-effects.
3. Leonard Seymour, a professor of gene therapy at Oxford University, whohas been working on the virus therapy with colleagues in London and the US, willlead the trials later this year. Cancer Research UK said yesterday that it wasexcited by the potential of Prof Seymour's pioneering techniques.
4. One of the country's leading geneticists, Prof Seymour has been workingwith viruses that kill cancer cells directly, while avoiding harm to healthytissue. "In principle, you've got something which could be many times moreeffective than regular chemotherapy," he said.
5. Cancer-killing viruses exploit the fact that cancer cells suppress thebody's local immune system. "If a cancer doesn't do that, the immune systemwipes it out. If you can get a virus into a tumour, viruses find them a verygood place to be because there's no immune system to stop them replicating. Youcan regard it as the cancer's Achilles' heel."
6. Only a small amount of the virus needs to get to the cancer. "Theyreplicate, you get a million copies in each cell and the cell bursts and theyinfect the tumour cells adjacent and repeat the process," said Prof Seymour.
7. Preliminary research on mice shows that the viruses work well on tumoursresistant to standard cancer drugs. "It's an interesting possibility that theymay have an advantage in killing drug-resistant tumours, which could be quitedifferent to anything we've had before."
8. Researchers have known for some time that viruses can kill tumour cellsand some aspects of the work have already been published in scientific journals.American scientists have previously injected viruses directly into tumours butthis technique will not work if the cancer is inaccessible or has spreadthroughout the body.
9. Prof Seymour's innovative solution is to mask the virus from the body'simmune system, effectively allowing the viruses to do what chemotherapy drugs do- spread through the blood and reach tumours wherever they are. The big hurdlehas always been to find a way to deliver viruses to tumours via the bloodstreamwithout the body's immune system destroying them on the way.
10. "What we've done is make chemical modifications to the virus to put apolymer coat around it - it's a stealth virus when you inject it," he said.
11. After the stealth virus infects the tumour, it replicates, but thecopies do not have the chemical modifications. If they escape from the tumour,the copies will be quickly recognised and mopped up by the body's immunesystem.
12. The therapy would be especially useful for secondary cancers, calledmetastases, which sometimes spread around the body after the first tumourappears. "There's an awful statistic of patients in the west ... with malignantcancers; 75% of them go on to die from metastases," said Prof Seymour.
13. Two viruses are likely to be examined in the first clinical trials:adenovirus, which normally causes a cold-like illness, and vaccinia, whichcauses cowpox and is also used in the vaccine against smallpox. For safetyreasons, both will be disabled to make them less pathogenic in the trial, butProf Seymour said he eventually hopes to use natural viruses.
14. The first trials will use uncoated adenovirus and vaccinia and will bedelivered locally to liver tumours, in order to establish whether the treatmentis safe in humans and what dose of virus will be needed. Several more years oftrials will be needed, eventually also on the polymer-coated viruses, before thetherapy can be considered for use in the NHS. Though the approach will beexamined at first for cancers that do not respond to conventional treatments,Prof Seymour hopes that one day it might be applied to all cancers.接下来为大家介绍"述说雅思阅读模拟练习：New weapon to fight cancer"
雅思阅读模拟练习：New weapon to fight cancer
Do the following statements agree with the information given in the readingpassage? For questions 1-6 write
TRUE if the statement agrees with the information
FALSE if the statement contradicts the information
NOT GIVEN if there is no information on this in the passage
1.Virus therapy, if successful, has an advantage in eliminatingside-effects.
2.Cancer Research UK is quite hopeful about Professor Seymour’s work on thevirus therapy.
3.Virus can kill cancer cells and stop them from growing again.
4.Cancer’s Achilles’ heel refers to the fact that virus may stay safely ina tumor and replicate.
5.To infect the cancer cells, a good deal of viruses should be injectedinto the tumor.
6.Researches on animals indicate that virus could be used as a new way totreat drug-resistant tumors.
Based on the reading passage, choose the appropriate letter from A-D foreach answer.
7.Information about researches on viruses killing tumor cells can befound
(A) on TV
(B) in magazines
(C) on internet
(D) in newspapers
8.To treat tumors spreading out in body, researchers try to
(A) change the body’ immune system
(B) inject chemotherapy drugs into bloodstream.
(C) increase the amount of injection
(D) disguise the viruses on the way to tumors.
9.When the chemical modified virus in tumor replicates, the copies
(A) will soon escape from the tumor and spread out.
(B) will be wiped out by the body’s immune system.
(C) will be immediately recognized by the researchers.
(D) will eventually stop the tumor from spreading out.
Complete the sentences below. Choose your answers from the list of words.You can only use each word once.
NB There are more words in the list than spaces so you will not use themall.
In the first clinical trials, scientists will try to ……10…… adenovirus andvaccinia, so both the viruses will be less pathogenic than the ……11…….Theseuncoated viruses will be applied directly to certain areas to confirm safety onhuman beings and the right ……12…… needed. The experiments will firstly be……13……to the treatment of certain cancers
List of Words
dosage responding smallpox virus
disable natural ones inject
directed treatment cold-like illness
kill patients examined
IELTS reading needs more practice.An article,New weapon to fight cancer, is not enough.We hope that the majority of candidates continue to work hard.
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